The Best Simvastatin Muscle References. Myopathy sometimes takes the form of rhabdomyolysis with or without acute renal failure secondary to myoglobinuria, and rare fatalities have occurred. Although not all of these side effects may occur, if they do occur they may need medical attention.

Data from clinical trials show these symptoms usually only occur in about 5% more patients taking statins compared to placebo (sugar pill). Muscle stiffness and weakness also occur to a varying degree. Merative, micromedex ® along with its needed effects, a medicine may cause some unwanted effects.